Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.6
USERS' SCORE
Good
Based on 9 Reviews
8.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Lactobacillus acidophilus (La-14)
2 Billion CFU
*
Top Medical Research Studies
9
L. acidophilus shows promise against Candida
We examined how Lactobacillus acidophilus ATCC 4356 can impact Candida albicans, the fungus responsible for yeast infections.
In our research, we studied both in vitro and in vivo. We found that L. acidophilus not only curbed biofilm formation and filamentation of C. albicans but also improved survival rates in Galleria mellonella larvae infected with this yeast.
The larvae given L. acidophilus showed fewer C. albicans, suggesting this probiotic strain might be beneficial in combating yeast infections.
In our research, we studied both in vitro and in vivo. We found that L. acidophilus not only curbed biofilm formation and filamentation of C. albicans but also improved survival rates in Galleria mellonella larvae infected with this yeast.
The larvae given L. acidophilus showed fewer C. albicans, suggesting this probiotic strain might be beneficial in combating yeast infections.
Read More
9
Probiotics reduce Candida biofilm growth
We explored how various Lactobacillus probiotics affect the development of Candida albicans biofilms, which are crucial for yeast infections. Through several tests, we observed that Lactobacillus strains significantly reduced biofilm growth and changed the behavior of the yeast, promoting a less harmful budding growth instead of filamentation. Specifically, early biofilm stages were notably impacted, indicating a potential role for these probiotics in managing yeast infections. However, the mature biofilm showed resistance to these treatments, suggesting limitations in probiotic effectiveness.
Read More
We investigated how cell-free supernatants from various Lactobacillus strains—particularly L. acidophilus, L. plantarum, L. rhamnosus, and L. reuteri—affect the harmful yeast Candida parapsilosis. Our study demonstrated that these lactobacilli not only inhibited the yeast’s ability to thrive but also bolstered the resistance of vaginal cells against infection. These findings suggest that incorporating these beneficial bacteria could help prevent infections linked to this fungi. However, further research is necessary to fully understand these complex mechanisms.
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Most Useful Reviews
10
Effective prevention method
42 people found this helpful
Great for preventing yeast infections. I suffered from severe yeast infections almost monthly, particularly when on antibiotics. Three years ago, I started this probiotic and haven't had a yeast infection since, even while taking antibiotics. It's definitely worth trying for anyone dealing with chronic yeast infections!
Read More
10
Significant improvement
9 people found this helpful
A Must Have. I will use this forever; it resolved my yeast and bacterial infections within a month. I used to experience watery discharge, but that issue has been eliminated since I've been using this product. My digestive system has also greatly improved. I received it very quickly too, which is a plus.
Read More
9
Promotes good yeast
9 people found this helpful
Works excellently. We use this product to combat bad yeast and promote good yeast. If you're taking antibiotics, it's essential to have acidophilus to prevent a yeast infection. My 89-year-old father has diabetes and takes two of these daily to manage his bad yeast levels. Excellent product at a very good price here on Amazon.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.6
- All Researches
9
We assessed the impact of a combination of Lactobacillus acidophilus, Lactobacillus rhamnosus, and lactoferrin on recurring yeast infections in women. In our study, 48 women received either the probiotic mixture or a placebo alongside standard treatment with clotrimazole. While both groups reported symptom improvement, those receiving the probiotics experienced significantly less itching and discharge after three and six months. Importantly, recurrence rates were markedly lower in the probiotic group, suggesting this combination could effectively manage recurrent vulvovaginal candidiasis.
Read More
9
We explored how consuming cheese enhanced with probiotics, specifically Lactobacillus acidophilus and Lactobacillus rhamnosus, impacts oral Candida levels in denture wearers. In our study, 60 participants were divided into three groups—two test groups receiving probiotic cheeses and a control group with regular cheese—over a period of eight weeks.
After the experiment, we observed a significant reduction in Candida levels in those eating probiotic cheese compared to the control group. This indicates that these probiotics could play a valuable role in lowering the risk of oral candidiasis among individuals who wear dentures.
After the experiment, we observed a significant reduction in Candida levels in those eating probiotic cheese compared to the control group. This indicates that these probiotics could play a valuable role in lowering the risk of oral candidiasis among individuals who wear dentures.
Read More
9
Probiotics reduce Candida biofilm growth
We explored how various Lactobacillus probiotics affect the development of Candida albicans biofilms, which are crucial for yeast infections. Through several tests, we observed that Lactobacillus strains significantly reduced biofilm growth and changed the behavior of the yeast, promoting a less harmful budding growth instead of filamentation. Specifically, early biofilm stages were notably impacted, indicating a potential role for these probiotics in managing yeast infections. However, the mature biofilm showed resistance to these treatments, suggesting limitations in probiotic effectiveness.
Read More
9
L. acidophilus shows promise against Candida
We examined how Lactobacillus acidophilus ATCC 4356 can impact Candida albicans, the fungus responsible for yeast infections.
In our research, we studied both in vitro and in vivo. We found that L. acidophilus not only curbed biofilm formation and filamentation of C. albicans but also improved survival rates in Galleria mellonella larvae infected with this yeast.
The larvae given L. acidophilus showed fewer C. albicans, suggesting this probiotic strain might be beneficial in combating yeast infections.
In our research, we studied both in vitro and in vivo. We found that L. acidophilus not only curbed biofilm formation and filamentation of C. albicans but also improved survival rates in Galleria mellonella larvae infected with this yeast.
The larvae given L. acidophilus showed fewer C. albicans, suggesting this probiotic strain might be beneficial in combating yeast infections.
Read More
9
Lactobacilli may prevent yeast infections
We assessed the effectiveness of two specific lactobacillus strains, Lactobacillus fermentum LF10 and Lactobacillus acidophilus LA02, in preventing recurrent vulvovaginal candidiasis (yeast infections).
In our clinical trial, 58 women received an initial treatment of fluconazole followed by a regimen of slow-release vaginal tablets containing these lactobacilli.
After a careful observation period, we found that those who maintained healthy symptoms showed promising results in fighting off yeast infections. This strengthens the role of specific lactobacilli in maintaining a healthy vaginal environment.
In our clinical trial, 58 women received an initial treatment of fluconazole followed by a regimen of slow-release vaginal tablets containing these lactobacilli.
After a careful observation period, we found that those who maintained healthy symptoms showed promising results in fighting off yeast infections. This strengthens the role of specific lactobacilli in maintaining a healthy vaginal environment.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
10
Effective prevention method
42 people found this helpful
Great for preventing yeast infections. I suffered from severe yeast infections almost monthly, particularly when on antibiotics. Three years ago, I started this probiotic and haven't had a yeast infection since, even while taking antibiotics. It's definitely worth trying for anyone dealing with chronic yeast infections!
Read More
10
Significant improvement
9 people found this helpful
A Must Have. I will use this forever; it resolved my yeast and bacterial infections within a month. I used to experience watery discharge, but that issue has been eliminated since I've been using this product. My digestive system has also greatly improved. I received it very quickly too, which is a plus.
Read More
9
Promotes good yeast
9 people found this helpful
Works excellently. We use this product to combat bad yeast and promote good yeast. If you're taking antibiotics, it's essential to have acidophilus to prevent a yeast infection. My 89-year-old father has diabetes and takes two of these daily to manage his bad yeast levels. Excellent product at a very good price here on Amazon.
Read More
9
Balanced well-being
4 people found this helpful
They WORK!!! I'm not usually one to write reviews, but I must say this product is brilliant. I was searching for something to help maintain a healthy balance for us women, and this is it. I take three a day on an empty stomach, and it has kept me perfectly balanced. I previously suffered from yeast infections due to antibiotics disrupting my balance. Since I started taking these, I haven't had one infection. I highly recommend this product.
Read More
9
Quick resolution
4 people found this helpful
Awesome product! I wish I had known about it sooner. After years of dealing with yeast infections, I took this for one month and it cleared up.
Read More
Frequently Asked Questions
9
Balanced well-being
4 people found this helpful
They WORK!!! I'm not usually one to write reviews, but I must say this product is brilliant. I was searching for something to help maintain a healthy balance for us women, and this is it. I take three a day on an empty stomach, and it has kept me perfectly balanced. I previously suffered from yeast infections due to antibiotics disrupting my balance. Since I started taking these, I haven't had one infection. I highly recommend this product.
7
In examining 15 studies from 2015 to 2020, we focused on whether Lactobacillus probiotics could help combat Candida yeast infections, which are common among women.
Our findings revealed that certain strains, including L. acidophilus, can significantly reduce the growth of these harmful fungi.
Notably, longer use of these probiotics correlates with better results, especially when paired with traditional treatments. Overall, Lactobacillus probiotics appear to be a promising alternative in managing yeast infections.
Our findings revealed that certain strains, including L. acidophilus, can significantly reduce the growth of these harmful fungi.
Notably, longer use of these probiotics correlates with better results, especially when paired with traditional treatments. Overall, Lactobacillus probiotics appear to be a promising alternative in managing yeast infections.
9
We assessed the impact of a combination of Lactobacillus acidophilus, Lactobacillus rhamnosus, and lactoferrin on recurring yeast infections in women. In our study, 48 women received either the probiotic mixture or a placebo alongside standard treatment with clotrimazole. While both groups reported symptom improvement, those receiving the probiotics experienced significantly less itching and discharge after three and six months. Importantly, recurrence rates were markedly lower in the probiotic group, suggesting this combination could effectively manage recurrent vulvovaginal candidiasis.
2
We conducted a multicenter double-blind trial to see if oral probiotics could help prevent recurrent vulvovaginal infections in pregnant women. After treating participants for existing infections, we split them into two groups—one receiving probiotics and one a placebo—until delivery.
Unfortunately, the results showed no significant difference in VVI rates between the two groups. Many women still experienced infections despite taking the probiotics for months. Ultimately, this study suggests that the tested probiotics did not effectively reduce the recurrence of these infections during pregnancy.
Unfortunately, the results showed no significant difference in VVI rates between the two groups. Many women still experienced infections despite taking the probiotics for months. Ultimately, this study suggests that the tested probiotics did not effectively reduce the recurrence of these infections during pregnancy.
5
Probiotics less effective than fluconazole
We conducted a thorough investigation to see how effective probiotics, specifically Lactobacillus acidophilus, are at treating yeast infections compared to fluconazole.
In a study with 80 women diagnosed with vulvovaginal candidiasis, we found that while probiotics showed some potential, fluconazole significantly outperformed them in reducing symptoms and preventing recurrence.
After treatment, the fluconazole group had lower rates of abnormal discharge and irritation compared to those taking probiotics. In essence, probiotics can help, but fluconazole is the more effective option for combating yeast infections.
In a study with 80 women diagnosed with vulvovaginal candidiasis, we found that while probiotics showed some potential, fluconazole significantly outperformed them in reducing symptoms and preventing recurrence.
After treatment, the fluconazole group had lower rates of abnormal discharge and irritation compared to those taking probiotics. In essence, probiotics can help, but fluconazole is the more effective option for combating yeast infections.
References
- Nachum Z, Suleiman A, Colodner R, Battino S, Wattad M, et al. Oral Probiotics to Prevent Recurrent Vulvovaginal Infections During Pregnancy-Multicenter Double-Blind, Randomized, Placebo-Controlled Trial. Nutrients. 2025;17. 10.3390/nu17030460
- ElFeky DS, Awad AR, Shamseldeen AM, Mowafy HL, Hosny SA. Comparing the therapeutic potentials of vs. against vulvovaginal candidiasis in female rats: an study. Front Microbiol. 2023;14:1222503. 10.3389/fmicb.2023.1222503
- Pimentel MMNSC, de Carvalho Alves J, Pinheiro LHS, Roselino MN. Potential Action of Probiotics Against Fungi of the Genus : A Bibliographic Review. Recent Pat Biotechnol. 2023;17:198. 10.2174/1872208317666221027093644
- Mollazadeh-Narestan Z, Yavarikia P, Homayouni-Rad A, Samadi Kafil H, Mohammad-Alizadeh-Charandabi S, et al. Comparing the Effect of Probiotic and Fluconazole on Treatment and Recurrence of Vulvovaginal Candidiasis: a Triple-Blinded Randomized Controlled Trial. Probiotics Antimicrob Proteins. 2023;15:1436. 10.1007/s12602-022-09997-3
- Spaggiari L, Sala A, Ardizzoni A, De Seta F, Singh DK, et al. Lactobacillus acidophilus, L. plantarum, L. rhamnosus, and L. reuteri Cell-Free Supernatants Inhibit Candida parapsilosis Pathogenic Potential upon Infection of Vaginal Epithelial Cells Monolayer and in a Transwell Coculture System . Microbiol Spectr. 2022;10:e0269621. 10.1128/spectrum.02696-21
- Kamal Y, Kandil M, Eissa M, Yousef R, Elsaadany B. Probiotics as a prophylaxis to prevent oral candidiasis in patients with Sjogren's syndrome: a double-blinded, placebo-controlled, randomized trial. Rheumatol Int. 2020;40:873. 10.1007/s00296-020-04558-9
- Er S, İstanbullu Tosun A, Arık G, Kıvanç M. Anticandidal activities of lactic acid bacteria isolated from the vagina. Turk J Med Sci. 2019;49:375. 10.3906/sag-1709-143
- Russo R, Superti F, Karadja E, De Seta F. Randomised clinical trial in women with Recurrent Vulvovaginal Candidiasis: Efficacy of probiotics and lactoferrin as maintenance treatment. Mycoses. 2019;62:328. 10.1111/myc.12883
- Russo R, Edu A, De Seta F. Study on the effects of an oral lactobacilli and lactoferrin complex in women with intermediate vaginal microbiota. Arch Gynecol Obstet. 2018;298:139. 10.1007/s00404-018-4771-z
- Miyazima TY, Ishikawa KH, Mayer M, Saad S, Nakamae A. Cheese supplemented with probiotics reduced the Candida levels in denture wearers-RCT. Oral Dis. 2017;23:919. 10.1111/odi.12669
- do Carmo MS, Noronha FM, Arruda MO, Costa ÊP, Bomfim MR, et al. ATCC 23271 Displays Inhibitory Activities against spp. Front Microbiol. 2016;7:1722.
- Matsubara VH, Wang Y, Bandara HMHN, Mayer MPA, Samaranayake LP. Probiotic lactobacilli inhibit early stages of Candida albicans biofilm development by reducing their growth, cell adhesion, and filamentation. Appl Microbiol Biotechnol. 2016;100:6415. 10.1007/s00253-016-7527-3
- Donders G, Bellen G, Neven P, Grob P, Prasauskas V, et al. Effect of ultra-low-dose estriol and lactobacilli vaginal tablets (Gynoflor®) on inflammatory and infectious markers of the vaginal ecosystem in postmenopausal women with breast cancer on aromatase inhibitors. Eur J Clin Microbiol Infect Dis. 2015;34:2023. 10.1007/s10096-015-2447-1
- Vilela SF, Barbosa JO, Rossoni RD, Santos JD, Prata MC, et al. Lactobacillus acidophilus ATCC 4356 inhibits biofilm formation by C. albicans and attenuates the experimental candidiasis in Galleria mellonella. Virulence. 2015;6:29. 10.4161/21505594.2014.981486
- Kovachev SM, Vatcheva-Dobrevska RS. Local Probiotic Therapy for Vaginal Candida albicans Infections. Probiotics Antimicrob Proteins. 2015;7:38. 10.1007/s12602-014-9176-0
- Murina F, Graziottin A, Vicariotto F, De Seta F. Can Lactobacillus fermentum LF10 and Lactobacillus acidophilus LA02 in a slow-release vaginal product be useful for prevention of recurrent vulvovaginal candidiasis?: A clinical study. J Clin Gastroenterol. 2014;48 Suppl 1:S102. 10.1097/MCG.0000000000000225
- Mezzasalma V, Manfrini E, Ferri E, Boccarusso M, Di Gennaro P, et al. Orally administered multispecies probiotic formulations to prevent uro-genital infections: a randomized placebo-controlled pilot study. Arch Gynecol Obstet. 2017;295:163. 10.1007/s00404-016-4235-2
- Ishikawa KH, Mayer MP, Miyazima TY, Matsubara VH, Silva EG, et al. A multispecies probiotic reduces oral Candida colonization in denture wearers. J Prosthodont. 2015;24:194. 10.1111/jopr.12198
